In the world of animated satire, “Family Guy” has carved a niche for itself by lampooning celebrities with sharp wit and humor. Recently, a video by Watch Mojo highlighted the reactions of notable stars to their appearances on the show, ranging from amusement to offense.

Dwayne Johnson, the former WWE star turned Hollywood icon, took his parody in stride. He humorously participated in a scene where he simulated a comical moment between characters, demonstrating his status as a fan of the show. On the other hand, Dua Lipa embraced her mention in a joke, showcasing her playful side by reposting the scene on social media, while Khloe Grace Moretz expressed how a viral meme, inspired by “Family Guy,” negatively affected her self-esteem.

Rachel Bloom, creator of “Crazy Ex-Girlfriend,” was less amused by her show’s parody, feeling it conflated appreciation for her work with condescension. Cardi B and Tom Cruise, who have both been the subject of the show’s humor, responded with grace, showcasing their ability to laugh at themselves. Cruise even engaged in a playful back-and-forth with Seth MacFarlane, the show’s creator.

The reactions weren’t all lighthearted. Celebrities like Sarah Palin and Adrien Brody expressed displeasure over their portrayals, with Brody revealing lingering hard feelings despite MacFarlane’s attempts to assuage any offense. Carol Burnett went so far as to sue the show for copyright infringement, although her case was ultimately dismissed, underscoring the fine line between satire and personal affront.

As “Family Guy” continues to push boundaries, the mixed reactions from celebrities reflect the complex nature of humor in pop culture. Whether they laugh along or take offense, these interactions highlight the show’s enduring influence and the conversations it sparks about celebrity culture.