Nathan Ake was taken off the pitch on a stretcher after sustaining a serious injury on international duty with the Netherlands.

The Manchester City defender started for Ronald Koeman‘s side in a 2-2 Nations League draw with Germany on Tuesday.

Tijjani Reijnders got the hosts off to a perfect start in Amsterdam before Deniz Undav equalised to put Germany back on level pegging.

With the Dutch looking to restore their lead on the brink of the interval Ake pulled up with what appeared to be a hamstring strain as he attempted to control the ball in the opposition half.

The severity of the situation was immediately apparent as the referee waved over the medical team to attend to the 29-year-old.

Nathan Ake appeared to suffer a serious injury playing for the Netherlands on Tuesday night

The Manchester City defender was distraught as he removed from the pitch on a stretcher in the Netherlands’ 2-2 draw with Germany

After initially attempting to return to his feet, a clearly emotional Ake was then removed from the pitch on a stretcher and replaced by Arsenal’s Jurrien Timber.

Joshua Kimmich then gave Julian Nagelsmann’s the lead before half-time before Denzel Dumfries made it 2-2.

Ake’s injury will come as a headache for Pep Guardiola, as his side face a busy fixture schedule following the international break.

The Premier League champions will look to continue their perfect start to the season when they play host to Brentford on Saturday.

The 29-year-old will now face an anxious wait to find out the severity of his injury

Then just four days later they get their European campaign underway at home to Inter Milan in the revamped Champions League.

Arsenal then visit the Etihad in a game that could prove to have significant implications on the title race come the end of the season.